Stem Cell Treatment for Cosmetic Rejuvenation

Stem Cell Treatments for Cosmetic Rejuvenation: Wrinkles, Laser Damage, or Aging are Currently Available at SIRM

Stem Cells for Cosmetic RejuvenationAs a Pioneer in Stem Cell Based Cosmetic Procedures, SIRMI continues our Tradition by providing Total Body Rejuvenation Packages with your Stem Cell Therapies.

Stem Cell Total Body Rejuvenation Package:

  • Anti-Aging Stem Cell Package includes IV stem Cells for total body rejuvenation
  • PRP Stem Cell Injections
  • Botulinum toxin fine-wrinkle injections
  • Custom-Compounded Autologous Facial Creams for the Patient (must be a patient)

Contact us today for our current specials






Stem Cell Treatment for Cosmetic Rejuvenation

Related Articles Glypican-based drug releasing titania implants to regulate BMP2 bioactivity as a potential approach for craniosynostosis therapy. Nanomedicine. 2018 10;14(7):2365-2374 Authors: Bariana M, Dwivedi P, Ranjitkar S, Kaidonis JA, Losic D, Anderson PJ Abstract Advances in molecular biology and nanomedicine based therapies hold promise to obviate the need of multiple surgical interventions (associated with current management) in craniosynostosis by preventing bone re-ossification. One such adjunctive therapy involves application of glypicans 1 and 3 (GPC1 and GPC3) that are BMP inhibitors implicated in downregulating the BMP2 activity in prematurely fusing sutures. Electrochemically anodized Titania nanotube (TNT) arrays have been recognized as a promising localized, long-term drug delivery platform for bone-related therapies. This study presents the application of nanoengineered TNT/Ti implants loaded with recombinant glypicans for craniosynostosis therapy. By using Dual luciferase Reporter assay, we tested the biofunctionality of eluted glypicans from the TNT/Ti implants for BMP2 bioactivity regulation in C2C12 murine myoblast cell line. BMP2 activity was inhibited significantly for up to 15days by the glypicans released from polymer-coated TNT/Ti implants, indicating their potential application in adjunctive craniosynostosis treatment. PMID: 28648641 [PubMed - indexed for MEDLINE]
Related Articles A 3D human placenta-on-a-chip model to probe nanoparticle exposure at the placental barrier. Toxicol In Vitro. 2019 Feb;54:105-113 Authors: Yin F, Zhu Y, Zhang M, Yu H, Chen W, Qin J Abstract With the commercialization of nanomaterials, environmental exposure to nanoparticles (NPs) has raised great concerns due to the long-term effects to human body, particularly to pregnant women. Previous studies found that NPs had an adverse impact on placenta in mice, but care must be taken when extrapolating the results to human pregnancy in consideration of the great difference between species. Here, we proposed a microengineered 3D placental barrier-on-a-chip microdevice and further explored complicated placental responses to NPs exposure in vitro. The microdevice recreated near-physiological 3D microenvironment and dynamic conditions in fetal maternal circulation combined with the extracellular matrix and flow. With the exposure to titanium dioxide nanoparticles (TiO2-NPs), a common nanomaterial, a series of placental responses were investigated, including oxidative stress, cell apoptosis, barrier permeability, and maternal immune cell behavior. By contrast to oxidative stress and cell apoptosis, placental barrier integrity and maternal immune cells were greatly influenced even with low concentrated NPs, suggesting the potential damages triggered by NPs in our daily life. Collectively, this in vitro experimental model of human placenta provides a simple platform to study environmental exposure to NPs, and might be potential for a wide range of applications in biological study, disease treatment and drug assessment. PMID: 30248392 [PubMed - indexed for MEDLINE]

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