Stem Cell Treatment for Rejuvenation

Related Articles Computational Strategies for Niche-Dependent Cell Conversion to Assist Stem Cell Therapy. Trends Biotechnol. 2019 Feb 16;: Authors: Del Sol A, Okawa S, Ravichandran S Abstract The field of regenerative medicine has blossomed in recent decades. However, the ultimate goal of tissue regeneration - replacing damaged or aged cells with healthy functioning cells - still faces a number of challenges. In particular, better understanding of the role of the cellular niche in shaping stem cell phenotype and conversion would aid in improving current protocols for stem cell therapies. In this regard, the implementation of novel computational approaches that consider the niche effect on stem cells would be valuable. Here we discuss current problems in stem cell transplantation and rejuvenation, and we propose computational strategies to control niche-dependent cell conversion to overcome them. PMID: 30782480 [PubMed - as supplied by publisher]

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