Stem Cell Treatments for Regenerative Medicine FAQ:

​Quick Overview:

We can attempt to treat your condition using your own (autologous) stem cells via Mobilizing your Peripheral Blood and/or Adipose derivation. For mobilizing stem cells from the bone marrow to the peripheral blood, we use human G-CSF (Neupogen/filgrastim). It is our hope to help you see improvement, no matter how large or small; however the results cannot be guaranteed. Each patient is unique and thus each patient will respond differently to treatment.

Treatments are either over 1-2 days or divided into 4-5 days(or longer) depending on your isolated cellular counts and treatment method(s) chosen.

For Mobilized Peripheral Blood:

  • Day 1-4: Consultation/Exam, Nutritional Supplementation (IV, IM, and Oral), Preparation and Mobilization of Peripheral blood via injections with Granulocyte-Colony Stimulating Factor (G-CSF). This aims to increase the number of stem cells in the bone marrow and mobilize these stem cells from the bone marrow to your peripheral blood
  • Day 3-4: Calculation to assure a sufficient number of mobilized cells is reached, we then harvest the stem cells via the Blood, which is then isolated and processed in Laboratory.
  • Day 4 or 5: The processed cells are re-infused systemically intravenously, and/or locally via Intraarticular, Intramuscular, Intranasal, Retrobulbar, or Intervertebral administration.

The cost of the treatments vary between ₱1,000,000 - ₱2,000,000, while specialized injections and additional specialists or infusions incur an additional cost. Fees are inclusive of airport transfers, and accommodation at one of the many nearby resort/hotels.

A 25% deposit is required to book and reserve an appointment. The earliest dates available are normally 1-month after a deposit is received. A Cardio-Pulmonary (CP) clearance, Complete blood count (CBC), Platelet count, and Erythrocyte Sedimentation Rate (ESR) is required for approval.

Should you require more information, feel free to contact us anytime.

 

Stem Cell Treatments for Regenerative Medicine

Mobilized Peripheral Blood and Stem Cell Therapy

 

Stem Cell Treatment Institute

We mobilize Stem Cells from Bone Marrow using G-CSF, and then using these stem cells, we treat a variety of Degenerative Conditions.

  1. The best source of stem cells
  2. How many days does the therapy take?
  3. What are the costs?
  4. What is Platelet Rich Plasma?

Mobilized Bone Marrow Stem Cells are the most research-based stem cells, are harvested without any invasive surgical procedures and appear to be the Best source of Stem Cells For Therapy and Treatment at this time.

The best and most research-based source of autologous adult stem cells:

  1. Mobilized Peripheral Blood (Cells mobilized from Bone marrow) which does not require surgery nor extraction by an Orthopedic Surgeon; blood is drawn from the patient (similar to a blood donation), cells are isolated and given back to the patient to treat various conditions (autologously).

Of all stem cells, those that are autologous involves the least risk. By definition, autologous cells are obtained from one's own body, just as one may bank his or her own blood for elective surgical procedures.

Do you offer Bone Marrow Stem Cell Harvesting? No, this is not longer needed, is invasive, exposes patients to pain and risk of infection, and less stem cells are obtained as opposed to Mobilized Peripheral Blood using G-CSF.

How long does the treatment take?

Treatments take from 3-5 days as patients are provided G-CSF for 3-4 days to mobilize the cells to the periphery and then these cells are harvested, isolated and provided as treatment.

What are the costs?

Fees Vary as each treatment and each patient are different. Please contact us directly to assess what would be the best treatment for you.

Platelet Rich Plasma (PRP) and Stem Cell Treatment

  1. PRP Injections
  2. What are the Potential Benefits of Treatment?
  3. Maximizing the benefits
  4. PRP Components

Platelet Rich Plasma (PRP): While not allowed to be mixed with Stem Cells in the USA, we do in fact provide this here in the Philippines at SIRM. PRP Contains the growth factors and platelets from blood which signal the body to send in stem cells to repair the area of injury. These concentrated platelets and bioactive proteins, including growth factors, are vital to initiate and accelerate tissue repair and regeneration, promote development of new blood vessels, and stimulate the wound healing process.

  • Platelet Rich Plasma (PRP) is the volume of the plasma fraction of autologous blood, containing a platelet concentration above baseline of 200,000 platelets/ul.

Platelet Rich Plasma therapy is being applied towards the facilitation of healing muscle, tendons, ligaments, articular and meniscal injuries. Its treatment options include various painful injuries and conditions with increasing frequency and effectiveness, such as arthritis of the hip, knee, shoulder, ankle and other joints.  PRP is also utilized for soft tissue injuries such as tendonitis, muscle sprains and tears, and various types of ligament injuries, such as tennis and golfers’ elbow, Achilles tendonitis and knee tendonitis.  PRP is also used to treat various injuries and conditions affecting (joint) injuries, such as rotator cuff and meniscus injuries. The number of injections given is patient-specific and depends upon the severity and the type of condition being treated.


To Maximize the PRP benefits: Refrain from smoking and alcohol intake since both diminish stem cell release. Discontinue for about 4-6 weeks the use of anti-inflammatory drugs -Advil, Aleve, Motrin, ibuprofen.- since they may diminish the inflammatory reaction caused by the PRP and well needed for a good result. The use of Omega 3-fish oil and other natural anti-inflammatory agents do not seem to work the same way and are thus not restricted.

Growth Factor Components of PRP:

  • TGF-αβ Transforming growth factor alpha & beta
  • EGF Epidermal growth factor
  • PDEGF Platelet derived epidermal growth factor
  • FGF Fibroblast growth factor
  • IGF Insulin growth factor
  • PDAF Platelet derived angiogenesis factor
  • IL-8 Interleuking-8
  • TNF-α Tumor necrosis factor alpha
  • CTGR Connective tissue growth factor)
  • GM-CSF Granulocyte macrophage colony stimulating factor
  • KGF Keratinocyte growth factor
  • OTHERS:
  • High concentration of leukocytes (neutrophils, eosinophils) for microbicidal events
  • High concentration of wound macrophages and other phagocytic cells, for biological debridement
  • Histamines, Serotonin, ADP, Thromboxane A2, and other vasoactive and chemotactic agents
  • High platelet concentration and native fibrinogen concentration for improved hemostasis

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